Publications
Publications

Publications (2010-2023)

  1. E.H. Hammami, N. Mérindol, M. B.-Plourde, M. Taisonnet, S. Level, L. Berthoux. 2023. SUMO-3 promotes the proteasomal targeting of TRIM55. Biochem Cell Biol. Published online Sept 13.
  2. Elfayres, R.J. Paswan, L. Sika, M.P. Girard, S. Khalfi, C. Letanneur, K. Milette, A. Singh, G. Kobinger, L. Berthoux. 2023. Mammalian cells-based platforms for the generation of SARS-CoV-2 virus-like particles. J Virol Meth. 21:114835.
  3. DiLecce, N. Mérindol, M. Galarza Pérez, V. Karimzadegan, L. Berthoux, A. Boari, C. Zidorn, M. Vurro, G. Surico, I. Desgagné-Penix, A. Evidente. 2022. Biochemical Analyses of Bioactive Extracts from Plants Native to Lampedusa, Sicily Minor Island. Plants. 11(24):3447.
  4. P. Girard, N. Mérindol, L. Berthoux, I. Desgagné-Penix. 2022. Le pouvoir antiviral des alcaloïdes d’Amaryllidaceae contre les virus à ARN. Virologie. 26(6):431-450.
  5. Rancourt, I.B. Sanchez Carrillo, V.P. Parra Gutierrez, M. B. Plourde, V. Fourcassié, S. Bourassa, A. Droit, L. Berthoux, H. Germain. 2021. Plantago asiatica mosaic virus infection and plant immune response impact Arabidopsis thaliana nuclear pore complexes. Nucleus. In revision.
  6. P. Girard, V. Karimzadegan, M. Héneault, F. Cloutier, G. Bérubé, L. Berthoux, N. Mérindol, I. Desgagné-Penix. 2022. Molecules. Chemical Synthesis and Biological Activities of Amaryllidaceae Alkaloid Norbelladine Derivatives and Precursors. 27(17):5621.
  7. Masi, R. Di Lecce, N. Mérindol, M.P. Girard, L. Berthoux, I. Desgagné-Penix, V. Calabrò, A. Evidente. 2022. Cytotoxicity and Antiviral Properties of Alkaloids Isolated from Pancratium maritimum. Toxins. 14(4):262.
  8. Ka, N. Merindol, I. Seck, S. Ricard, A. Diop, C. Boye, K. Landelouci, B. Daoust, L. Berthoux, G. Pépin, M. Seck, I. Desgagné-Penix. 2021. Biological investigation of Amaryllidaceae alkaloid extracts from the bulbs of Pancratium trianthum Herb. collected in the Senegalese flora. Molecules. 26(23):7382.
  9. Ka, N. Merindol, A. Sow, A. Singh, K. Landelouci, M. B. Plourde, G. Pépin, M. Masi, R. di Lecce, A. Evidente, M. Seck, L. Berthoux, L. Chatel-Chaix, I. Desgagné-Penix. 2021. Amaryllidaceae alkaloid cherylline inhibits the replication of dengue and Zika viruses. Antimicrob Agents Chemother. 65(9):e0039821.
  10. Klionsky et al. 2021. Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (4th edition). Autophagy. 17(1):1-382.
  11. Khalfi, N. Merindol, L. Berthoux. 2020. Fonctions cellulaires et antivirales de TRIM5α. Virologie. 24 (6):369-380.
  12. Désaulniers, L. Ortiz, C. Dufour, A. Claudel, M. B. Plourde, N. Merindol, L. Berthoux. 2020. Editing of the TRIM5 gene decreases the permissiveness of human T lymphocytic cells to HIV-1. Viruses. 13(1):E24.
  13. Berthoux. 2020. The restrictome of flaviviruses. Virol. Sin. 35(4): 363-377.
  14. Merindol, M. El-Far, M. Sylla, N. Masroori, C. Dufour, J-x Li, P. Cherry, M.B. Plourde, C. Tremblay, L. Berthoux. 2018. HIV-1 capsids from B27/B57+ elite controllers escape Mx2 but are targeted by TRIM5α, leading to the induction of an antiviral state. PLOS Path. 14:e1007398.
  15. Dufour, A. Claudel, N. Joubarne, N. Merindol, T. Maisonnet, N. Masroori, M.B. Plourde, L. Berthoux. 2018. Editing of the Human TRIM5 Gene to Introduce Mutations with the Potential to Inhibit HIV-1. PLOSone e0191709.
  16. Masroori, P. Cherry, N. Merindol, J.-x. Li, C. Dufour, L. Poulain, M.B. Plourde, L. Berthoux. 2017. Gene Knockout Shows That PML (TRIM19) Does Not Restrict the Early Stages of HIV-1 Infection in Human Cell Lines. mSphere e00233-17.
  17. -É. Nepveu-Traversy, A. Demogines, T. Fricke, M.B. Plourde, K. Riopel, M. Veillette, F. Diaz-Griffero, S.L. Sawyer, L. Berthoux. 2016. A putative SUMO interacting motif in the B30.2/SPRY domain of rhesus macaque TRIM5α important for NF-κB/AP-1 signaling and HIV-1 restriction. Heliyon e00056.
  18. Masroori, N. Mérindol, L. Berthoux. 2016. The interferon-induced antiviral protein PML (TRIM19) promotes the restriction and transcriptional silencing of lentiviruses in a context-specific,isoform-specific fashion. Retrovirology 13:19.
  19. Pizzato, M. Neagu, T. Pertel, C. Firrito, S. Ziglio, M. Zufferey, L. Berthoux, J. Luban. 2015. Lv4 is a capsid-specific antiviral activity in human blood cells that restricts viruses of the SIVmac/SIVsm/HIV-2 lineage prior to integration. P.L.O.S. Path. 16(11).
  20. Jung, K. Urak, M. Veillette, M.E. Nepveu-Traversy, Q.T. Pham, S. Hamel, J.J. Rossi, L. Berthoux. 2015. Preclinical assessment of mutant human TRIM5α as an anti-HIV-1 transgene. Hum. Gene Ther. 26:664-71.
  21. Mérindol, L. Berthoux. 2015. Restriction factors in HIV-1 disease progression (review). Curr. HIV Res. 13:448-61.
  22. Pawlica, C. Dufour, L. Berthoux. 2015. Inhibition of microtubules and dynein rescues HIV-1 from owl monkey TRIMCyp-mediated restriction in a cellular context-specific fashion. J. Gen. Virol. 96:874-86.
  23. Pawlica, L. Berthoux. 2014. Cytoplasmic dynein promotes HIV-1 uncoating. Viruses. 6:4195-211.
  24. Pawlica, V. LeSage, N. Poccardi, M.J. Tremblay, A.J. Mouland, L. Berthoux. 2014. Functional evidence for the involvement of microtubules and dynein complexes in TRIM5α-mediated restriction of retroviruses. J. Virol. 88:5661-76.2.
  25. -É. Nepveu-Traversy, L. Berthoux. 2014. The conserved sumoylation consensus site in TRIM5α modulates its immune activation functions. Virus Res. 184:30-8.
  26. Veillette, K. Bichel, P. Pawlica, S. M.V. Freund, M. B. Plourde, Q. T. Pham, L. C. James, L. Berthoux. 2013. The V86M mutation in HIV-1 Capsid Confers Resistance to TRIM5α by Abrogation of Cyclophilin A-Dependent Restriction and Enhancement of Viral Nuclear Import. Retrovirology, 10:25.
  27. T. Pham, M. Veillette, A. Brandariz-Nuñez, P. Pawlica, C. Thibert-Lefebvre, N. Chandonnet, F. Diaz-Griffero, L. Berthoux. 2013. A Novel Aminoacid Determinant of HIV-1 Restriction in the TRIM5α Variable 1 Region Isolated in a Random Mutagenic Screen. Virus Res 173:306-14.
  28. B. Plourde, A. Morchid, L. Iranezereza, L. Berthoux. 2013. The Bcl-XL/Bcl-2 inhibitor BH3I-2’ affects the stability and subcellular localization of sumoylated proteins. Int J Biochem Cell B. 45:826-35.
  29. Malbec, Q.T. Pham, M.B. Plourde, A. Létourneau-Hogan, M.-E. Nepveu-Traversy, L. Berthoux. 2010. Murine Double Minute 2 as a modulator of retroviral restrictions mediated by TRIM5α. Virology 405:414-23.
  30. T. Pham, A. Bouchard, M.G. Grütter, L. Berthoux. 2010. Generation of human TRIM5α mutants with high HIV-1 restriction activity. Gene Ther. 17:859-71.
  31. -X. Yang, V. Guen, J. Richard, E.A. Cohen, L. Berthoux. 2010. Cell context-specific involvement of ATR in early stages of retroviral replication. Virology 396:272-9.