Publications récentes

Fisette A, Sergi D, Breton-Morin A, Descôteaux S, Martinoli MG (2022). New insights on the role of bioactive food derivatives in neurodegeneration and neuroprotection. Curr Pharmaceut. Des., Vol. 28, No. 37, 2022. doi: https://doi.org/10.2174/1381612828666220919085742. PMID: 36121075

G. Costa, F. F. Caputi, M. Serra, N. Simola, L. Rullo, S. Stamatakos, F. Sanna, M. Germain, M-G. Martinoli, S. Candeletti, M. Morelli and P. Romualdi (2021). Activation of antioxidant and proteolitic pathways in the nigrostriatal dopaminergic system after 3,4-methylenedioxymethamphetamine (MDMA) administration: gender-related differences. Front. Pharmacol. 12:713486. doi: 10.3389/fphar.2021.713486.

D. Sergi, A. Gélinas, J. Beaulieu, J. Renaud, E. Tardif-Pellerin, J. Guillard and M-G. Martinoli. (2021) Anti-apototic and anti-inflammatory role of trans e-viniferin in a neuron –glia co-culture cellular model of Parkinsons’ disease. Foods 2021, 10(3), 586; doi.org/10.3390/foods10030586

J. Beaulieu, G. Costa, J. Renaud, A. Moitié, H. Glémet, D. Sergi, M-G. Martinoli. The neuroinflammatory and neurotoxic potential of palmitic acid is mitigated by oleic acid in microglial cells and microglial- neuronal co-cultures. (2021) Molecular Neurobiology 1-15, published on line Feb. 18^th, 2021, doi: 10.1007/s12035-021-02328-7

D. Sergi, J. Renaud, N. Simola and M-G. Martinoli. (2019) Diabetes, a contemporary risk for Parkinson’s disease: epidemiological and cellular evidences. Front Aging Neurosci. 2019 Nov 8;11:302. doi: 10.3389/fnagi.2019.00302. eCollection 2019. Invited review. PMID: 31787891.

J. Renaud and M-G. Martinoli. Considerations for the use of polyphenols in neurodegenerative diseases. Int. J. Mol. Sci. 2019, 20, 1883; doi:10.3390/ijms20081883 https://www.mdpi.com/1422-0067/20/8/1883

J. Renaud, N. Simola, M-G Martinoli. The sweet road to Parkinson’s disease. Invited Editorial, Aging, 2019, 11. https://www.ncbi.nlm.nih.gov/pubmed/30708352

D. Sergi, A. C. Morris, D. E. Kahn, F.H. McLean, P. Kibitz, M-G. Martinoli, J. E. Drew, L. M. Williams. Palmitic acid triggers inflammatory responses in neurons partially via ceramide synthesis but not via TLR4. Nut. Neurosci, 2018. https://doi.org/10.1080/1028415X.2018.1501533

J. Renaud, V. Bassareo, J. Beaulieu, A. Pinna, M. Schlich, C. Lavoie, D. Murtas, N. Simola, M.-G. Martinoli (2018). Dopaminergic neurodegeneration in a rat model of long-term hyperglycemia: preferential degeneration of the nigrostriatal motor pathway. Neurobiol. Aging, 69:117-128. DOI: 10.1016/j.neurobiolaging.2018.05.010

J. Renaud and M.-G. Martinoli. Prevention of neuroinflammation by resveratrol: Focus on experimental models and molecular mechanisms. Chapter 18 in “Neuroprotective Effects of Phytochemicals in Neurological disorders". Eds: T. Farooqui and A. Farooqui. DOI: 10.1002/9781119155195.ch18, pp.377-394, (2017).

S. Touj, S. Houle, D. Ramla, R. Jeffrey-Gauthier, H. Hotta, G. Bronchti, M.-G. Martinoli, M. Piché. Sympathetic regulation and anterior cingulate cortex morphology are altered in a rat model of chronic back pain. Neuroscience, vol. 352, pp. 9–18, (2017).

E. Attard and M.-G. Martinoli. What are the Prospects of Treating Neurodegenerative Diseases with Natural Products? EC Neurology 7.1: pp. 26-33, (2017).

I. Achour, A.-M. Arel-Dubeau, J. Renaud, M. Legrand, E. Attard, M. Germain and M.-G. Martinoli. Oleuropein prevents neuronal death, mitigates mitochondrial superoxide production and modulates autophagy in a dopaminergic cellular model. International Journal of Molecular Sciences, vol. 17, no. 1293, (2016).

J. Renaud and M.-G. Martinoli. Setting up an insert co-culture system to assess cellular changes mediated by secreted soluble factors in the absence of cell-cell contact. Journal of Visualized Experiments, no. 113, e54356, (2016).

J. Renaud, H.-M. Thérien, M. Plouffe, M.-G. Martinoli. La neuroinflammation : Dr Jekyll ou Mr Hyde ? Médecine/Sciences, no. 31, pp. 979-988, (2015).

E. Attard and M.-G. Martinoli. Cucurbitacin E, an experimental lead triterpenoid with anticancer, immunomodulatory and novel effects against degenerative diseases: A mini-review. Current Topics in Medicinal Chemistry, vol. 15, no. 17, pp.1708-1713, (2015). Invited review.

J. Renaud, S. F. Nabavi, M. Daglia, S. M. Nabavi and M.-G. Martinoli. Epigallocatechin-3-gallate, a  promising molecule for Parkinson's disease. Rejuvenation Research, vol. 18, no. 3, pp.257-269, (2015).

A.-M. Arel-Dubeau, F. Longpré, J. Bournival, C. Tremblay, J. Demers-Lamarche, P. Haskova, E. Attard, M. Germain, and M.-G. Martinoli. Cucurbitacin E Has Neuroprotective Properties and Autophagic Modulating Activities on Dopaminergic Neurons. Oxidative Medicine and Cellular Longevity, vol. 2014, article ID 425496, 15 pages, (2014).

C. Provencher, A. Bertolo, P. Magnan, M.-G. Martinoli. Modulation of Specific Apoptotic DNA Fragmentation after Short Term Exposure to Natural UVR in Fish Larvae. Open Journal of Apoptosis, vol. 3, pp. 39-51, (2014).

J. Renaud and M.-G. Martinoli. Resveratrol as a protective molecule for neuroinflammation: a review of mechanisms. Current Pharmaceutical Biotechnology, vol. 15, no. 4, pp. 318-329, (2014).

J. Renaud, J. Bournival, X. Zottig and M.-G. Martinoli. Resveratrol protects neuronal PC12 cells against high glucose-induced oxidative stress and apoptosis : effect on p53 and GRP75 localization. Neurotoxicity Research, vol. 25, no. 1, pp.110-123, (2014).

J. Renaud, K. Chiasson, J. Bournival, C. Rouillard and M.-G. Martinoli. 17β-estradiol delays 6-OHDA-induced apoptosis by acting on Nur77 translocation from the nucleus to the cytoplasm. Neurotoxicity Research, vol. 25, no. 1, pp.124-134, (2014).

J. Bournival, M. Plouffe, J. Renaud, C. Provencher and M.-G. Martinoli. Quercetin and sesamine protect dopaminergic cells from MPP+-induced  neuroinflammation in a microglial (N9)-neuronal (PC12) co-culture system. Oxidative Medicine and Celluler Longevity, article ID 921941, 11 pages, doi: 10.1155/2012/921941, (2012).

J. Bournival, M.-A. Francoeur, J. Renaud and M.-G.Martinoli. Quercetin and sesamin protect dopaminergic neurons from high-glucose-induced oxidation, nitrosative stress and apoptosis. Rejuvenation Research, vol. 15, no. 3, pp.322-333, (2012).

J. Ismaili, M. Boisvert, F. Longpré, J. Carange, C. Le Gall, M.-G. Martinoli and B. Daoust. Brassinosteroids and analogs as neuroprotectors: synthesis and structure activity. Steroids, vol. 77, pp.91-99, (2012).

J. Renaud et M.-G. Martinoli. Propriétés neuroprotectrices, antioxydantes et anti-inflammatoires du resveratrol sur les neurones dopaminergiques. Médecine-Sciences Am. vol. 1, no. 1, invited paper, (2012).

J. Carange, F. Longpré, B. Daoust and M.-G. Martinoli. 24-Epibrassinolide, a phytosterol fron the brassinosteroid family, protects dopaminergic cells against MPP+- induced oxidative stress and apoptosis. J. Toxicol. vol. 201, Article ID 392859, 13 pages. doi: 10.1155/2011/392859, (2011).

V. Boily, A. Bertolo, P. Magnan, M.-G. Martinoli and H.-M. Therien. Effects of ultraviolet radiation quality and instensity on yellow perch larvea (perca flavescens). Aquatic Sciences, Vol. 73, pp. 345-354, (2011).

J. Bournival, P. Quessy and M.-G. Martinoli. Protective effects of resveratrol and quercetin against MPP+-induced oxidative stress act by modulating markers of apoptotic death in dopaminergic neurons. Cell. Mol. Neurobiol. vol. 29, pp. 1169-1180 (2009).

V. Lahaie-Collins, J. Bournival, M. Plouffe, J. Carange and M.-G. Martinoli. Sesamin modulates tyrosine hydroxylase, superoxide dismutase, catalase, inducible NO Synthase and Interleukin-6 Expression in Dopaminergic Cells Under MPP⁺-Induced Oxidative Stress. Oxidative Medicine and Cellular Longevity, vol. 1, no. 1, pp. 54–62, invited paper (2008).

J. Blanchet, F. Longpré, G. Bureau, M. Morissette, T. DiPaolo, G. Bronchti and M.-G. Martinoli. Resveratrol, a red wine polyphenol protects dopaminergic neurons in MPTP-treat mice. Prog. Neuro-Psychoph. vol. 32, no. 5 pp.1243-50 (2008).

G. Bureau, F. Longpré and M.-G. Martinoli. Resveratrol and quercetin, two natural polyphenols, reduce apoptitotic neuronal cell death induced by neuroinflammation. J. Neurosci. Res. vol. 86, pp 403-410 (2007).

K. Chiasson, V. Lahaie-Collins, J. Bournival, B. Delapierre, S. Gélinas and M.-G. Martinoli. Oxidative stress and 17-a and 17-b estradiol modulate neurofilaments differently. J. Molec. Neurosci. 30(3): 297-310. PMID: 17401155, (2006).

K. Chiasson, B. Daoust, D. Levesque and M.-G. Martinoli. Dopamine D2 agonists, bromocriptine and quinpirole, increase MPP+-induced toxicity in PC12 cells. Neurotoxicity Res., 10(1): 31-42. PMID: 17000468, (2006).

S. Gélinas, G. Bureau, B. Valastro, G. Massicotte, K. Chiasson, B. Gagné, J. Blanchet and M.-G. Martinoli. Alpha and beta estradiol protect neuronal but not native PC12 cells from paraquat-induced oxidative stress. Neurotoxicity Res., 6(2): 141-148. PMID: 15255966, (2004).

C. Ménard, B. Valastro, M.-A. Martel and M.-G. Martinoli. Strain-related variations of AMPA receptor modulation by calcium-dependent mechanisms in the hippocampus: contribution of lipoxygenase metabolites of arachidonic acid. Brain Res 1010: 134-143, PMID: 15126126, (2004).

N. Lapointe, M. St-Hilaire, M.-G. Martinoli, J. Blanchet, P. Gould, C. Rouillard, F. Cicchetti. Rotenone induces non-specific nervous system and systemic toxicity. The FASEB journal, 18(6):717-719; doi10.1096/fj.03-0677fje. PMID: 14766796, (2004).

B. Gagné, S. Gélinas, G. Bureau, B. Lagacé, C. Ramassamy, K. Chiasson, B. Valastro and M.-G. Martinoli. Effect of estradiol, phytoestrogens and gingko biloba extracts against MPP+-induced oxidative stress. Endocrine, special suppl. Estrogens and neuroprotection. 21(1): 89-95. Invited paper. PMID: 12777708, (2003).

M. Graham, L. Cossette, S. Gélinas and M.-G. Martinoli. In vitro modulation of prolactin mRNA by toxaphene and 3.3', 4.4' Tetrachlorobiphenyl. Environ. Res., 92(3): 207-212. PMID: 12804517, (2003).

L. Cossette, I. Gaumond and M.-G. Martinoli. Combined effect of xenoestrogens and growth factors in two estrogen-responsive cell lines. Endocrine. 18(3): 303-308. PMID: 12450323, (2002).

S. Gélinas and M.-G. Martinoli. Neuroprotective effet of estradiol and phytoestrogens on MPP+-induced cytotoxicity in neuronal PC12. J. neurosci. Res., 70(1): 90-96. PMID:12237867, (2002).

J. Rousseau, L. Cossette, S. Grenier and M.-G. Martinoli. Modulation of prolactin expression by xenoestrogens. J. Comp. Endo., 126(2): 175-182. PMID: 12030773, (2002).

S. Gélinas, C. Chapados, M. Beauregard, I. Gosselin and M.-G. Martinoli. Effect of oxidative stress on stability and structure of neurofilament proteins. Biochem Cell. Biol., 78(6): 667-674. PMID: 11206577, (2000).